General Information

  • ID:  hor007058
  • Uniprot ID:  P51671??25-97)
  • Protein name:  Eotaxin
  • Gene name:  IL18; IGIF, IL1F4;
  • Organism:  Homo sapiens
  • Family:  Intercrine beta (chemokine CC) family
  • Source:  Human
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
  • GO MF:  GO:0005576 extracellular region; GO:0005615 extracellular space
  • GO BP:  GO:0048018 receptor ligand activity; GO:0046983 protein dimerization activity; GO:0008009 chemokine activity; GO:0048020 CCR chemokine receptor binding; GO:0031728 CCR3 chemokine receptor binding
  • GO CC:  GO:0045766 positive regulation of angiogenesis; GO:0007611 learning or memory; GO:0006874 intracellular calcium ion homeostasis; GO:0006954 inflammatory response; GO:0070371 ERK1 and ERK2 cascade; GO:0048245 eosinophil chemotaxis; GO:0007010 cytoskeleton organization; GO:0006935 chemotaxis; GO:0060763 mammary duct terminal end bud growth; GO:0070098 chemokine-mediated signaling pathway; GO:0007155 cell adhesion; GO:0060444 branching involved in mammary gland duct morphogenesis; GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide; GO:0007015 actin filament organization; GO:0002544 chronic inflammatory response; GO:0002551 mast cell chemotaxis; GO:0030838 positive regulation of actin filament polymerization; GO:0009314 response to radiation; GO:0043547 positive regulation of GTPase activity; GO:0006468 protein phosphorylation; GO:0030335 positive regulation of cell migration; GO:0001938 positive regulation of endothelial cell proliferation; GO:0008360 regul

Sequence Information

  • Sequence:  PASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP
  • Length:  73
  • Propeptide:  MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP
  • Signal peptide:  MKVSAALLWLLLIAAAFSPQGLA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    NA

Physical Information

Mass: Formula:
Absent amino acids: Common amino acids:
pI: Basic residues:
Polar residues: Hydrophobic residues:
Hydrophobicity: Boman Index:
Half-Life: Half-Life Yeast:
Half-Life E.Coli: Aliphatic Index
Instability Index: Extinction Coefficient cystines:
Absorbance 280nm:

Literature

  • PubMed ID:  NA
  • Title:  NA